Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1198 | 1198-30925 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74V, L210W, T215Y | K219KE | K103NS, Y181C, G190A | K101Q, V118I, P119S, K122E, I135T, S162A, T200A, I202V, R211K, H221HY, L228LR, V245M |
| >1198-30925| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHP AGLQKSKSVTVLDVGDAYFSISLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQASMTKILEPFRKQNPDIVICQYMDDLYVASDLEIGQHRAKVEELRQHLWKWGFYTP DEKYQKEPPFRWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | L10FI, G73C | I13IM, K20I, N37S, K55R, R57K, Q61N, I62V, L63N, I64V, C67F, H69R, I72T, P79A, I85V |
| >1198-30925| codons 4-99 TLWQRPIVTMKIGGQLIEALLDTGADDTVLEEMSLPGRWKPKIIGGIGGFIRVKQYDNVN VEIFGRKATCTVLVGATPVNVVGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |