<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-1198 1198-30925 Argentina 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, L74V, L210W, T215Y K219KE K103NS, Y181C, G190A   K101Q, V118I, P119S, K122E, I135T, S162A, T200A, I202V, R211K, H221HY, L228LR, V245M  
>1198-30925| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLQKSKSVTVLDVGDAYFSISLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQASMTKILEPFRKQNPDIVICQYMDDLYVASDLEIGQHRAKVEELRQHLWKWGFYTP
DEKYQKEPPFRWMGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I84V, L90M L10FI, G73C I13IM, K20I, N37S, K55R, R57K, Q61N, I62V, L63N, I64V, C67F, H69R, I72T, P79A, I85V  
>1198-30925| codons 4-99
TLWQRPIVTMKIGGQLIEALLDTGADDTVLEEMSLPGRWKPKIIGGIGGFIRVKQYDNVN
VEIFGRKATCTVLVGATPVNVVGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006