Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1197 | 1197-30924 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54IM, V82A, L90M | L10F, K43KT, G73GS | I15V, L19Q, K20I, L63P, A71V, I72L, V77I, I93L |
| >1197-30924| codons 4-99 TLWQRPFVTIKVGGQQIEALLDTGADDTVLEEMNLPGRWTPKIIGGIGGFMKVRQYDQIP IEICGHKVLSTVLIGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR, Y115F, Q151M, M184MV | A62V, D67DG, V75I, F77L, F116Y | K103N, Y181C, G190A | K46Q, T58N, S68SR, R83RK, V111I, K122E, D123E, I135T, S162C, R211RIM, F214L |
| >1197-30924| codons 38-247 CTEMEKEGQISKIGPENPYNNPVFVIKRKGRTKWRKLIDLRELNKKTQDFWEVQLGIPHP AGLKKNKSVTVLDIGDAFYSVPLDEEFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP AIFQCSMTKILEPFRKQNPDIVICQYVDDLYVASDLEIGQHRTKIEELRQHLLMWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |