Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1115 | 1115-30716 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, M184V, L210W, T215Y | K103N | P225H | K122E, V189I, R211RK, L228LI, V245M |
| >1115-30716| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYIGSDLEIGQHRTKIEELRQHLWKWGFYTP DKKHQKEHPFIWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I50IV, I54IM, V82A, L90M | L23I, L33F, K43T, F53FL | T4S, L10I, L63P, H69Q, A71V, I85IV, I93L |
| >1115-30716| codons 4-99 SLWQRPIVTIKIGGQLKEAILDTGADDTVFEEMNLPGRWTPKIIGGVGGLMKVRQYDQIP IEICGQKVIGTVLVGPTPANIVGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |