Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1048 | 1048-30625 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | K103N | V108I | K43N, V60I, K102KR, V118VI, I135T, S162SC, T200TA, E203EK, R211K, K223E, L228R, I244IV, V245VE |
| >1048-30625| codons 38-247 CTELENEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKRNKSVTILDVGDAYFSIPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRAKIKELRQHLWKWGFYTP DKKHQEEPPFRWMGYELHPDKWTVQPVELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | F53FL, G73S | L10V, I15V, L19I, N37ND, K55KR, R57RK, D60E, I62V, L63P, A71V, I72IL |
| >1048-30625| codons 4-99 TLWQRPVVTIKVGGQIKEALLDTGADDTVLEEMDLPGRWKPKLIGGIGGLVRVKQYEQVP IEICGHKVLSTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |