Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1047 | 1047-30623 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K70R, T215F | D67H, K219Q | P225H | E44EA, V60I, W88S, V90I, D123E, I135T, S162Y, D177E, L187LS, T200A, E203D, R211KT |
| >1047-30623| codons 38-247 CTELEKAGKISKIGPENPYNTPIFAIKKKHSTRWRKLVDFRELNKRTQDFSEIQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKQNPEIVIYQYMDDSYVGSDLEIGQHRAKIDELRQHLLTWGFFTP DQKHQKEHPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, G73GS | K14KR, L63P, A71V, I72L, V77VI, I93L |
| >1047-30623| codons 4-99 TLWQRPFVTIRIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVRQYDQIP IEICGHKVLSTVLIGPTPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |