Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1044 | 1044-30617 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, M184V, L210W, T215Y | K103N, Y181C, G190A | T39K, K43E, E44D, K49KR, V118I, D123E, I135T, D177E, T200A, E203K, Q207E, H208F, R211K, K223T, V245Q |
| >1044-30617| codons 38-247 CKELEEDGKISRIGPENPYNTPVFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIVICQYVDDLYVASDLEIGQHRAKIKELREFLWKWGFYTP DKKHQTEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V, V82T, L90M | L23I, F53L, Q58E | L10I, I15V, K20R, E35D, M36I, N37D, K55R, R57K, D60E, I62V, L63P, A71V, I93L |
| >1044-30617| codons 4-99 TLWQRPIVTIKVGGQLREAILDTGADDTVLEDIDLPGRWKPKIIGGIGGLIRVKEYEQVP IEICGHKVIGTVVVGPTPTNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |