<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-1044 1044-30617 Argentina 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L76V, V82T, L90M L23I, F53L, Q58E L10I, I15V, K20R, E35D, M36I, N37D, K55R, R57K, D60E, I62V, L63P, A71V, I93L  
>1044-30617| codons 4-99
TLWQRPIVTIKVGGQLREAILDTGADDTVLEDIDLPGRWKPKIIGGIGGLIRVKEYEQVP
IEICGHKVIGTVVVGPTPTNIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, M184V, L210W, T215Y   K103N, Y181C, G190A   T39K, K43E, E44D, K49KR, V118I, D123E, I135T, D177E, T200A, E203K, Q207E, H208F, R211K, K223T, V245Q  
>1044-30617| codons 38-247
CKELEEDGKISRIGPENPYNTPVFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPEIVICQYVDDLYVASDLEIGQHRAKIKELREFLWKWGFYTP
DKKHQTEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006