Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1173 | 1173-30930 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, V75M, M184V, L210LW, T215F | K219HQ | K103N, G190A | V108I | V60I, V111I, D121H, K122E, I135T, E169D, D177E, I178L, H208Y, R211Q, I244IM |
| >1173-30930| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTILDIGDAYFSVPLHEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILDPFRKQNPELVIYQYVDDLYVASDLEIGQHRTKIEELRQYLWQWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPMVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54IV, L76V, V82T | L10F | T4TS, L19I, K20R, M36I, R41K, I62IV, L63P, I64M, A71V, I72T, L89LM, I93L |
| >1173-30930| codons 4-99 SLWQRPFVTIKIGGQIREALLDTGADDTVLEEINLPGKWKPKIIGGIGGFVKVRQYDQVP MEICGHKVTGTVVVGPTPTNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |