Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1187 | 1187-30918 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, T215CNSY | K219KE | Y181YC, G190A | K49KR, D123E, I135T, I142IT, D177E | Y232H |
| >1187-30918| codons 38-247 CTELEKEGKISRIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIVICQYMDDLYVASDLEIGQHRTKIEELRQHLLRWGFYTP DEKHQKEPPFLWMGHELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48V, I54AV, V82A, L90M | F53L | L10I, T12S, I15IV, N37E, K55R, I62IV, L63P, A71I, V77I, I93L |
| >1187-30918| codons 4-99 TLWQRPIVSIKVGGQLKEALLDTGADDTVLEEMELPGRWKPKLIVGIGGLVRVRQYDQVP IEICGHKIIGTVLIGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |