Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1168 | 1168-30911 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219N | K103N, Y181C | V179VF | E44D, E53D, V118I, K122KE, I135L, I142V, A158AS, S162Y, E194ED, R211K, F214FC, L228LR | K220KE |
| >1168-30911| codons 38-247 CTELEKDGKISKIGPDNPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSLNNETPGVRYQYNVLPQGWKGSP SIFQYSMTKILEPFRKQNPDIFICQYMDDLYVGSDLDIGQHRTKIEELRQHLWKWGCYTP DNEHQKEPPFRWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, I84V | F53L | L10V, T12E, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, A71V, T74S, I85V, L89I |
| >1168-30911| codons 4-99 TLWQRPVVEIKVGGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGLVKVKQYDNIL IEICGHKVIGSVLVGPTPANVVGRNILTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |