Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1167 | 1167-30903 | Argentina | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, I84V, L90M | G73T | L10I, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, L63P, I85IV |
| >1167-30903| codons 4-99 TLWQRPIVTIKVGGQLREALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFVKVKQYDNIP IEICGHKAITTVLVGPTPVNVVGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | V60I, K122E, I135V, V179VI, V245L |
| >1167-30903| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPILLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |