Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1088 | 1088-30820 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, L210W, T215Y | L100I, K103N | E44D, A98S, D123E, I135T, Q174K, D177E, Q207E, R211K, D237E, V245M |
| >1088-30820| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP SGIKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKKNPEIVIYQYMDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTP DKKHQKEPPFLWMGYELHPEKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, V82A, L90M | T12E, I15V, L19I, R57K, L63P, A71V, T74S |
| >1088-30820| codons 4-99 TLWQRPLVEIKVGGQIKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVKQYDQIP IEICGHKVIGSVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |