Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1086 | 1086-30715 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219N | K103N | T39K, K43E, E44D, A98S, V118I, K122E, K166R, D177N, G196E, T200A, E203K, H208Y, R211K, K223E, L228H, V245M |
| >1086-30715| codons 38-247 CKELEEDGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP SGLKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPNIVIYQYVDDLYVGSDLEIEQHRAKIKELRQYLWKWGFYTP DNKHQEEPPFHWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | L10F, G73ST | K20I, E35D, M36I, N37D, I62V, L63P, A71V, P79A |
| >1086-30715| codons 4-99 TLWQRPFVTIKIGGQLIEALLDTGADDTVLEDIDLPGRWKPKIIGGIGGFIKVRQYDQVP IEICGHKVITTVLVGATPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |