Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1083 | 1083-30708 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K122E, E138A, I142T, T200V, R211K, V245LM | D113DN |
| >1083-30708| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGNAYFSVPLDEDFRKYTAFTIPSINNATPGTRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRVKIEELRQHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54IT, L90M | G73C | L10R, T12K, L19I, K20I, L24*, E35D, I62V, L63P, I64V, I72V, V77I |
| >1083-30708| codons 4-99 TLWQRPRVKIKIGGQIIEAL*DTGADDTVLEDMNLPGRWKPKIIGGIGGFTKVRQYDQVP VEICGHKAVCTVLIGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |