Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1017 | 1017-30618 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, M184V | K103N | R83K, V90I, K102N, I135V, E138A, S162A, I202IV, R211K, K238KI, V245Q |
| >1017-30618| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKKTQDFWEIQLGIPHP AGLKNNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSVNNATPGIRYQYNVLPQGWKGSP AIFQASMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKVEELRQHLLKWGFTTP DKKHQKEPPFLWMGYELHPDIWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82T, I84V | F53L | L10I, K20R, E35D, M36I, N37ND, R41RK, L63P, I66F, A71V |
| >1017-30618| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGLVKVRQYDQIP IEFCGHKVIGTVLVGPTPTNVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |