Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1009 | 1009-30618 | Argentina | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48GV, I54IV, V82VAFS | L10I, K14R, I15V, K20KR, E35D, M36I, N37D, R41K, R57K, Q61N, L63D, E65D, I66IV, I72IV, I93L |
| >1009-30618| codons 4-99 TLWQRPIVTIRVGGQLREALLDTGADDTVLEDIDLPGKWKPKMIVGIGGFVKVKQYDNID IDVCGHKAVGTVLVGPTPSNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70KR, L74V, Y115YF, M184V | D67DA, K219KE | T39A, D123DE, I135V, I159IV, S162C, T200A, D218DE |
| >1009-30618| codons 38-247 CAEMEKEGKISKIGPENPYNTPVFAIKKKASTRWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAFFSVPLDKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AVFQCSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGFTTP EEKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |