Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1067 | 1067-30617 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, I84V, L90M | L10F, G73T | I13V, G16A, A22V, N37ND, R41RK, I62V, L63P, C67F, H69R, A71V, I72L, V77VI, N83S, T91TS, I93L |
| >1067-30617| codons 4-99 TLWQRPFVTVKIAGQLKEVLLDTGADDTVLEEMDLPGKWKPKIVGGIGGFVKVRQYDQVP IEIFGRKVLTTVLIGPTPVSVIGRNLMSQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | K219N | K103N | K238T | E44D, V118I, K122E, D123DN, I142IT, S162C, I178IM, T200A, E203K, Q207DE, H208Y, R211K, K223Q, L228H |
| >1067-30617| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHRAKIKELREYLWKWGFYTP DNKHQQEPPFHWMGYELHPDTWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |