Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1010 | 1010-30611 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I47V, I54M, L90M | L10F, L33F, L89V | K14R, I15V, K20T, E35N, M36I, R41Q, A71V, I72T, G73D, I85V, I93L |
| >1010-30611| codons 4-99 TLWQRPFVTIRVGGQLTEALLDTGADDTIFENINLPGQWKPKMVGGIGGFMKVRQYDQIL IEICGHKVTDTVLVGPTPVNIVGRNVMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, K70R, M184V, T215TFIS | K219Q | K103N, Y181C | A98G | T69N, V118I, I135T, R211K, F214L, L228R |
| >1010-30611| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHP GGLKKNKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGLSTP DQKHQKEPPFRWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |