<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-1064 1064-30611 Argentina 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y   K103N, Y181C   K43KQ, E44D, V60I, K64R, V118I, K122E, I135T, E138EQ, G196Q, Q197QK, T200A, I202V, Q207E, R211RK, E224DN D110DN
>1064-30611| codons 38-247
CTELEQDGKISKIGPENPYNTPIFAIRKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSVTVLNVGDAYFSIPLDEDFRKYTAFTIPSTNNQTPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVGSDLEIQKHRAKVEELREHLWKWGFYTP
DKKHQKNPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46IL, I54V, V82A, L90M V11VI, L33F, K43T, G73S L10I, I13V, L24F, E34Q, K55R, D60E, I62V, L63P, A71V, I72K, V77I, I93L  
>1064-30611| codons 4-99
TLWQRPIITVKIGGQLKEALFDTGADDTVFQEMNLPGRWTPKLIGGIGGFVRVRQYEQVP
IEICGHKVKSTVLIGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006