Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1006 | 1006-30609 | Argentina | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, V82S | G73C | L10I, I15V, G16E, K20R, E35D, M36I, R41E, R57K, Q61N, I62V, I72R, I93L |
| >1006-30609| codons 4-99 TLWQRPIVTIKVEGQLREALLDTGADDTVLEDINLPGEWKPKMIVGIGGFVKVKQYDNVL IEICGHKARCTVLVGPTPSNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DN, K70KR, T215TFIS | K219KE | Y181YC, G190GA | K101KHNQ | T39IL, V60VI, S68SG, K122KE, I135V, S162CY, R211RK, L228LH |
| >1006-30609| codons 38-247 CLEMEKEGKISKIGPENPYNTPIFAIKKKNGTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLQKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKQNPDIVICQYMDDLYVASDLEIGQHRTKIEELRQHLLKWGFSTP DEKHQKEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |