Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1001 | 1001-30609 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, M184V, T215F | K219Q | Y181YC, Y188L, G190GA | K101KHNQ | V60VI, K122P, I135T, I142IV, I178IFL, V179VI, G196GE, F214L, L228LH |
| >1001-30609| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLQKKKSVTVLDVGDAYFSVPLDPDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDLIICQYVDDLLVASDLEIEQHRTKIEELRQHLLRWGLFTP DQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I84V | L10F, L33I, L89V | I13V, M36ML, N37C, K55R, R57RK, L63P, H69Q, A71T, Q92R |
| >1001-30609| codons 4-99 TLWQRPFVTVKIGGQLKEALLDTGADDTVIEELCLPGRWKPKLIGGIGGFIRVKQYDQIP IEICGQKTIGTVLVGPTPVNVIGRNVLTRIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |