Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1023 | 1023-30623 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L24I, Q58QE | L10I, K20KR, L33X, E35DN, M36I, N37E, P39Q, I62V, L63P, A71V, T91S |
| >1023-30623| codons 4-99 TLWQRPIVTIKIGGQLREALIDTGADDTVFENIELQGRWKPKLIGGIGGFVKVREYDQVP IEICGHKVIGTVLVGPTPANIIGRNLLSQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69DE, L74I, M184V, L210W, T215Y | K219R | K103KN | P225H | E44D, D123E, R211K, D218E |
| >1023-30623| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSEKWRKIVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTP ERKHQKEHPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |