Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1135 | 1135-30729 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, Q151M | A62AV, V75I, F77L, F116Y, K219KE | K101EQ, Y181C, G190A | I135IT, S162SHNR, V245M |
| >1135-30729| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKNSTKWRKLIDLRELNKRTQDFWEVQLGIPHP AGLQKKKSVTVLDVGDAYYSVPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP AIFQRSMTKILEPFRKQNPDIVICQYMDDLYVASDLEIGQHRTKIEELRQHLLRWGFTTP DEKHQKEPPFLWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, V82VA | L24LI, Q58QE | L10I, I62IV, L63PS, I64IV, V77I, I93IL |
| >1135-30729| codons 4-99 TLWQRPIVTIKIGGQLKEALIDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVREYDQVS VEICGHKAIGTVLIGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |