Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1137 | 1137-30729 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184MV, L210W, T215Y | K103N, Y181C, G190GA | A98G, V179F | E44D, D86DN, K101R, K122E, I135V, E194EQ, G196E, H208HY, D218DE, L228LR |
| >1137-30729| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQNFWEVQLGIPHP GGLRKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIFICQYVDDLYVASDLQIEQHRTKIEELRQYLWRWGFYTP EKKHQKEPPFRWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54S, V82A, L90M | L33F | L10I, T12V, I13V, E34Q, N37DE, I62V, L63PS, A71I, V77I, I93L |
| >1137-30729| codons 4-99 TLWQRPIVVVKIGGQLKEALLDTGADDTVFQEMELPGRWKPKMIVGIGGFSKVRQYDQVS IEICGHKIIGTVLIGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |