Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1134 | 1134-30724 | Argentina | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, T12K, I15V, G16GE, M36I, N37D, R41K, R57K, Q61N, L63I, I72T, I93L |
| >1134-30724| codons 4-99 TLWQRPIVKIKVEGQLKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVKQYDNII IEICGHKATGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74LV, M184V | K219KQ | K103N | K238T | T69TN, I135L, K173N, Q197K, T200E, Q207E, L210F |
| >1134-30724| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSNKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRNQNPDIVIYQYVDDLYVGSDLEIGKHREKIEELREHLFRWGFTTP DQKHQKEPPFLWMGYELHPDTWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |