Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1033 | 1033-30922 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L210W, T215Y | Y181C, G190GS | E44D, K101Q, K104R, V118I, K122E, D123E, I135V, K173R, V189VI, Q207E, R211K, L228H, V245E |
| >1033-30922| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLQKKRSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRRQNPDIVICQYMDDLYISSDLEIGQHRTKIEELREHLWKWGFYTP DKKHQKEPPFHWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, I84V | L24I, K43T | L10I, I15V, K20R, E35D, M36I, N37D, I62V, L63P, A71AV, I72V, T74A |
| >1033-30922| codons 4-99 TLWQRPIVTIKVGGQLREALIDTGADDTVLEDIDLPGRWTPKLIGGIGGFVKVRQYDQVP IEICGHKVVGAVLVGPTPANVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |