Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1051 | 1051-30630 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69TADN, L74LI, L210W, T215Y | K219N | K101E, Y181I, G190GS | K43KQ, E44D, V118I, D123E, S162D, V179VI, H208Y, R211K, D218DE, L228H |
| >1051-30630| codons 38-247 CTELEQDGKISKIGPENPYNTPVFAIKKKNSNKWRKIVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQDSMTKILEPFRKQNPDIIIIQYMDDLYVSSDLEIGQHRTKIEELRQYLWKWGFYTP ENKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48V, I54T, V82A | L33F | L10I, L19I, N37CS, L63P, A71V, V77I, L89LIM, I93IL |
| >1051-30630| codons 4-99 TLWQRPIVTIKIGGQIKEALLDTGADDTVFEEMSLPGRWKPKLIVGIGGFTKVRQYDQIP IEICGHKVIGTVLIGPTPANIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |