Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1192 | 1192-30929 | Argentina | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I50IV, I54V, L76LV, V82A | L33LF, Q58E | L10IV, G16GE, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, L63T, E65D, I72T, L89M |
| >1192-30929| codons 4-99 TLWQRPVVTIKIEGQLREALLDTGADDTVFEDINLPGKWKPKIIGGVGGFVRVKEYDNIT IDICGHKATGTVVVGPTPANIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74LV, T215F | Y181C, G190A | A98AG, V108VI | K101Q, V106VL, I135V, I142V, I178M, V189VI, R211Q, L228R |
| >1192-30929| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHP GGLQKKKSLTILDVGDAYFSVPLDKDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDMVICQYMDDLYIASDLEIGQHRTKIEELRQHLLQWGFFTP DKKHQKEPPFRWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |