Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1166 | 1166-30903 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54ILM, V82A, I84IV, L90M | V11VI, L33F, Q58E | L10I, T12K, I13V, L19I, K20R, M36I, N37D, L63P, I72V, L89F |
| >1166-30903| codons 4-99 TLWQRPIIKVKIGGQIREALLDTGADDTVFEEIDLPGRWKPKLIGGIGGFMKVREYDQIP IEICGHKAVGTVLVGPTPANVIGRNFMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | V75I | L100I, K103N | K122P, I135T, I142V, K166R, D177E, V179I, I202V |
| >1166-30903| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKLIDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSVPLDPDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPEIIIYQYMDDLYVGSDLEIGQHRTKVEELRQHLWRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |