Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1075 | 1075-30626 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, L74V, T215F | K219Q | K101KE, Y181C, G190GA | V108VI | T39A, K122KE, D123X, I135IM, S162SC, D177E, D218E |
| >1075-30626| codons 38-247 CAEMEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTILDVGDAYFSVPLDEXFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPEIVICQYMDDLYVASDLEIGQHRTKIEELRQHLLRWGFFTP EQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L33F, F53L, T74PS | L10I, I13V, I15IV, G16A, K20V, E35D, M36I, R41K, K55KR, R57K, Q61N, L63AV, A71V, I93L |
| >1075-30626| codons 4-99 TLWQRPIVTVKVAGQLVEALLDTGADDTVFEDINLPGKWKPKMIGGIGGLVRVKQYDNIV IEICGHKVIGSVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |