Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1015 | 1015-30618 | Argentina | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54IV, V82A | L24I, L33F, G73GC | L10I, I15V, K20T, E35DN, M36I, R41K, K55R, R57K, Q61N, L63P, I93L |
| >1015-30618| codons 4-99 TLWQRPIVTIKVGGQLTEALIDTGADDTVFENINLPGKWKPKIIGGIGGFVRVKQYDNIP IEICGHKAICTVLVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, T215Y | Y181C, G190A | K101H | T39AE, E44D, V60VI, V90VI, K122E, I135V, I142V, D177N, V179VI, T200A, R211T, D218DE |
| >1015-30618| codons 38-247 CEELEKDGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEIQLGIPHP AGLHKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPNIIICQYMDDLYVASDLEIGQHRAKIEELRQHLLTWGFYTP EKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |