<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1608 1608-30522 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, L210W, T215Y K219R Y181C, G190A A98G, V108I, F227L E44D, K64KN, K101Q, V118I, K122E, V179I, T200TA, E203K, Q207E, H208Y, R211K, K223E, L228R, V245T  
>1608-30522| codons 38-247
CTELEKDGKISKIGPENPYNTPVFAINKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
GGLQKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIIICQYMDDLYVASDLEIGQHRAKIKELREYLWKWGFYTP
DRKHQEEPPLRWMGYELHPDKWTVQPITLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54L, I84V, L90M L33F, G73C L10I, K20R, E34N, E35D, M36I, P39S, K55KR, I62V, L63P, A71T, I72IT, V77VI, I93L  
>1608-30522| codons 4-99
TLWQRPIVTIKIGGQLREALLDTGADDTVFNDINLSGRWKPKMIGGIGGFLRVRQYDQVP
IEICGHKTTCTVLIGPTPVNVIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006