Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1607 | 1607-30519 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | K103N, G190A | K49R, A98S, K122E, D123N, K166I, D177N, I195L, T200A, R211K, V245E |
| >1607-30519| codons 38-247 CTEMEKEGKISRIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP SGLKKNKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTIILEPFRKQNPNIVIYQYMDDLYVASDLELGQHRAKIEELRQHLLKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L24I | I15V, K20R, E35D, M36I, N37D, K55R, R57K, D60E, I62V, L63P, I64V |
| >1607-30519| codons 4-99 TLWQRPLVTIKVGGQLREALIDTGADDTVLEDIDLPGRWKPKLIGGIGGFVRVKQYEQVP VEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |