Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-3030 | 3030-30312 | Canada | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, T215F | D67G, K219Q | K103N | S68G, V90I, K122E, D123N, I135IL, S162SN, V179I, G196E |
| >3030-30312| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKGGTRWRKLVDFRELNKRTQDFWEIQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP AIFQNSMTKILEPFRKQNPDIIIYQYMDDLYVGSDLEIEQHRTKIEELRQHLLRWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | L24I, Q58QE | L10I, K20R, M36I, R41K, I62V, L63T, I64V, E65D |
| >3030-30312| codons 4-99 TLWQRPIVTIKIGGQLREALIDTGADDTVLEEINLPGKWKPKIIGGIGGFVKVREYDQVT VDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |