<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-3028 3028-30311 Canada 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, V75T, M184V, T215Y A62V, K219N G190T A98G K43KE, E44EA, K122E, I135T, Q197EK, E203K, Q207E, H208Y, K223Q, L228H, V245Q W212L
>3028-30311| codons 38-247
CTELEEAGKISKIGPENPYNTPVFVIKKKDSTKWRKVTDFRELNKRTQDFWEVQLGIPHP
GGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVTSDLEIGKHRTKIKELREYLLRLGFYTP
DNKHQQEPPFHWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54M, V82A, L90M L33F, G73S L10I, L24*, E34Q, R41K, K55R, D60E, I62V, L63P, I66L, K70R, A71V, V77I  
>3028-30311| codons 4-99
TLWQRPIVTIKIGGQLKEAL*DTGADDTIFQEMNLPGKWKPKIVGGIGGFMRVRQYEQVP
IELCGHRVISTVLIGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006