Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-3026 | 3026-30306 | Canada | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, T215F | K219E | T39A, T69N, V90VI, D123DE, I178M, V179I, H208Y, R211K, D218E, K223R, L228H |
| >3026-30306| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKKKNSNRWRKLVDFRELNKRTQDFWEIQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDMIIYQYVDDLYVGSDLEIGQHRTKIEELRQYLLKWGFFTP EEKHQREPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I84V, L90M | Q58E | L10I, K20KR, E35D, M36I, N37A, K55R, R57K, I62V, L63P, I93IL |
| >3026-30306| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVLEDIALPGRWKPKLIGGIGGFIRVKEYDQVP IEICGHKAIGTVLVGPTPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |