<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-3112 3112-30529 Canada 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T L24I L10I, K20KR, E35D, M36L, N37D, K55R, I62V, L63P, I64V, T74S  
>3112-30529| codons 4-99
TLWQRPIVTIKIGGQLREALIDTGADDTVLEDLDLPGRWKPKIIGGIGGFVRVRQYDQVP
VEICGHKAIGSVLVGPTPTNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, L74V, M184V, T215F K219Q Y181C, G190S K101H T39A, V60VI, V118I, K122E, S162D, E169D, V179I, R211K, F214L, D218E, L228H, Q242QH I159L
>3112-30529| codons 38-247
CAELEKEGKISKIGPENPYNTPIFAIKKKNSDRWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLHKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
ALFQDSMTKILDPFRKQNPDIIICQYVDDLYVSSDLEIGQHRTKIEELRQHLLKWGLFTP
EQKHQKEPPFHWMGYELHPDKWTVHPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006