Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-3041 | 3041-30313 | Canada | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, V75T, Y115F, M184V | A62V, T215D | L100I, K103N | S48SP, V118I, D123E, I135T, T200A, I202V, V245M |
| >3041-30313| codons 38-247 CTEMEKEGKIPKIGPENPYNTPVFVIKKKDSTKWRKVTDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAFFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRAKVEELRQHLLRWGFDTP DKKHQKEPPFLWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | Q58E, G73S | L10V, E35D, M36I, N37T, I62V, L63P, A71V, I72V, V77I |
| >3041-30313| codons 4-99 TLWQRPVVTIKIGGQLKEALLDTGADDTVLEDITLPGRWKPKMIGGIGGFIKVREYDQVP IEICGHKVVSTVLIGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |