Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-3038 | 3038-30311 | Canada | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10FI, Q58E, G73S | T12K, I13V, L19T, K20T, N37D, Q61R, L63P, A71V, I72L |
| >3038-30311| codons 4-99 TLWQRPIVKVKIGGQTTEALLDTGADDTVLEEMDLPGRWKPKIIGGIGGFVKVREYDRIP IEICGHKVLSTVLVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | A62V, V75I, F77L, F116Y | K103N | S68G, T69I, V118I, I135T, T200L, R211K, F214L |
| >3038-30311| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKDGIKWRKLIDLRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYYSIPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRLKIEELRQHLLKWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |