<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-3083 3083-30613 Canada 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219N L100I, K103N A98G K43KN, E44D, V118I, K122E, D123N, I135V, I142V, S162C, G196E, H208Y, L228H, V245M  
>3083-30613| codons 38-247
CTELENDGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
GGIKKNKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSP
AIFQCSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIEQHRTKIEELRQYLWRWGFYTP
DNKHQKEPPFHWMGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V L24I, G73T L10Y, I13V, I15V, Q18QH, K20V, F53Y, Q61QH, L63P, V77VI  
>3083-30613| codons 4-99
TLWQRPYVTVKVGGHLVEALIDTGADDTVLEEMNLPGRWKPKIIGGIGGYVKVRQYDHIP
IEICGHKAITTVLIGPTPVNVIGRNLLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006