Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1613 | 1613-30714 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, L90M | L10I, L19Q, K20M, E35D, M36I, K43KR, I62V, L63H, I64V, V82VI, I85IV, I93L |
| >1613-30714| codons 4-99 TLWQRPIVTIKIGGQQMEALLDTGADDTVLEDINLPGRWRPKIIGGIGGFIKVRQYDQVH VEICGHKAIGTVLVGPTPINIVGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74LV | K219Q | K103KN, Y181YC | V60VI, T69TNSY, K122KE, D218E, V245VM |
| >1613-30714| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKKNSYRWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTP EQKHQKEPPFLWMGYELHPDKWTVQPIMLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |