<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2062 2062-30623 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, V75M, M184V, L210W, T215Y K219N Y181C, G190A K101H, V108I, F227L T39E, E44D, V60I, K103R, V118I, K122E, D123N, I135T, I142V, D177EG, V189I, G196E, E203K, Q207E, H208Y, H221Y, K223E  
>2062-30623| codons 38-247
CEELEKDGKISKIGPENPYNTPIFAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHP
AGLHKRKSVTILDVGDAYFSIPLDENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPGIVICQYVDDLYIASDLEIEQHRTKIKELREYLWRWGFYTP
DNKYQEEPPLLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54L, L76V, I84V, L90M G73S, L89V L10I, V11L, I13V, I15V, Q18H, K20I, E34Q, E35D, M36I, N37ND, D60E, I62V, L63P, A71L, I72L, I93L  
>2062-30623| codons 4-99
TLWQRPILTVKVGGHLIEALLDTGADDTVLQDIDLPGRWKPKIVGGIGGFLKVRQYEQVP
IEICGHKLLSTVVVGPTPVNVIGRNVMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006