<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1736 1736-30418 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48AS, I54V, V82A, L90M K43T, G73S L10I, V11L, T12E, I15V, K20I, E35D, M36I, I62V, L63P, A71V, I72R, I85IV  
>1736-30418| codons 4-99
TLWQRPILEIKVGGQLIEALLDTGADDTVLEDINLPGRWTPKMISGIGGFVKVRQYDQVP
IEICGHKVRSTVLVGPTPANIVGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, Q151M, M184V, L210W A62V, T215E, K219Q Y188FL   K64H, T69N, V90VI, V111I, V118I, I135T, S162A, T165TI, R172K, D192H, R211RK, F214L, D218E, L228H, Q242QH, V245VE  
>1736-30418| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFVIHKKNSNRWRKLVDFRELNKRTQDFWEIQLGIPHP
AGLKKKKSVTVLDIGDAYFSIPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP
AIFQASMIKILEPFKKQNPDIVIYQYVDDLLVGSHLEIGQHRTKIEELRQHLWKWGLETP
EQKHQKEPPFHWMGYELHPDKWTVHPIELP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006