Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1602 | 1602-30528 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54L, L76V, I84V, L90M | L10F, V11I, G73S | I15V, K20I, E34Q, E35D, M36I, N37T, K55KR, R57K, I62V, L63P, A71V |
| >1602-30528| codons 4-99 TLWQRPFITIKVGGQLIEALLDTGADDTVLQDITLPGRWKPKIIGGIGGFLRVKQYDQVP IEICGHKVISTVVVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, M184V, L210W, T215Y | L100I, Y181I | A98G, V108I | E44D, K122E, I135T, I202IV, E203K, Q207D, H208Y, R211K, K223Q, L228H |
| >1602-30528| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP GGIKKKKSVTILDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIIQYVDDLYVGSDLEIGQHRTKVKELRDYLWKWGFYTP DKKHQQEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |