Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1600 | 1600-30702 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V | T215C, K219E | K103KN, Y181C | V60VI, V90VI, K102Q, K122KE, D123E, S162C, V179I, T200TA, I202V, H221HY, L228H | D113DN |
| >1600-30702| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEIQLGIPHP AGLKQNKSVTVLDVGNAYFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDIIICQYVDDLYVGSDLEIGQHRAKVEELRQHLLRWGFCTP DEKYQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46IV, I47V, I54M | L10F, L33F | L63LP, K70KE, A71V, V77VI, I85IV |
| >1600-30702| codons 4-99 TLWQRPFVTIKIGGQLKEALLDTGADDTIFEEMNLPGRWKPKVVGGIGGFMKVRQYDQIP IEICGHEVIGTVLIGPTPVNIVGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |