<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1726 1726-30502 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, G48V, I54S, V82A, L90M L33F, Q58E L10I, I13V, G16E, I62V, L63T, A71V, V77I, I93L  
>1726-30502| codons 4-99
TLWQRPIVTVKIEGQLKEALLDTGADDTVFEEMNLPGRWKPKLIVGIGGFSKVREYDQVT
IEICGHKVIGTVLIGPTPANIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70E, Y115F, Q151M A62V, V75I, F77L, F116Y V106A, G190GA   T39TA, T58N, V118I, K122E, Q174K, N175Y, I178M, L187F, G196K, Q197E, T200E, F214L, L228R, I244V, V245E T165TS
>1726-30502| codons 38-247
CAEMEKEGKISKIGPENPYNNPVFVIKKKNSTEWRKLIDLRELNKRTQDFWEVQLGIPHP
AGLKKKKSATVLDVGDAFYSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP
AIFQSSMSKILEPFRKKYPDMVIYQYMDDFYVASDLEIKEHREKIEELRQHLLRWGLTTP
DKKHQKEPPFRWMGYELHPDKWTVQPVELP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006