<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1725 1725-30501 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, M184V, T215F K219Q Y181C, G190A A98G, V179E T39E, K103R, V118I, K122E, I135T, I142IT, K173R, G196E, H208Y, R211K, F214L, L228H N137NH
>1725-30501| codons 38-247
CEELEKEGKISKIGPENPYNTPVFAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHP
GGLKKRKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNHETPGTRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRRQNPDIEICQYVDDLYVASDLEIEQHRTKIEELRQYLLKWGLFTP
DQKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54IV, I84V, L90M L10F, G73T I13M, K20I, A22V, M36MI, I62V, L63P, I64V, I66IV, V77I, N83NS, I85IV, I93IL  
>1725-30501| codons 4-99
TLWQRPFVTMKIGGQLIEVLLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYDQVP
VEVCGHKAITTVLIGPTPVSVVGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006