<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1650 1650-30324 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70R, M184V, L210W, T215Y T69G, K219D K103N, G190A   K43E, E44D, D67X, S68N, V118I, K173E, T200A, R211K, D218E, L228H, Q242H, V245E L246MT
>1650-30324| codons 38-247
CTELEEDGKISKIGPENPYNTPVFAIKKKXNGRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFREQNPDIVIYQYVDDLYVASDLEIGQHRAKIEELRQHLWKWGFYTP
EDKHQKEPPFHWMGYELHPDKWTVHPIETP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48M, I54V, V82A L24I, F53L L10I, K20KR, M36I, N37D, L63P, A71T  
>1650-30324| codons 4-99
TLWQRPIVTIKIGGQLREALIDTGADDTVLEEIDLPGRWKPKMIMGIGGLVKVRQYDQIP
IEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006