<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2012 2012-30612 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74V, T215F K219Q L100LI, Y181I, G190A   K43E, K49R, V60I, K101Q, V118I, K122E, S162D, V179I, I202V, H208Y, R211K, D218E, L228H, V245E  
>2012-30612| codons 38-247
CTELEEEGKISRIGPENPYNTPIFAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHP
AGIQKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQDSMTKILEPFRKQNPDIIIIQYMDDLYVASDLEIGQHRTKVEELRQYLLKWGFFTP
EQKHQKEPPFHWMGYELHPDKWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82F, I84V, L90M V11I, G73S, L89V L10I, I15V, Q18H, K20I, E35D, M36I, N37D, I62V, L63P, A71V, I72M, P79A, I85V  
>2012-30612| codons 4-99
TLWQRPIITIKVGGHLIEALLDTGADDTVLEDIDLPGRWKPKIIGGIGGFVKVRQYDQVP
IEICGHKVMSTVLVGATPFNVVGRNVMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006