Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1568 | 1568-30306 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, V82F | L10I, P39S, R57K, I62V, L63P, I64V, I72V, V77I, I85V |
| >1568-30306| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLSGRWKPKIVGGIGGFVKVKQYDQVP VEICGHKAVGTVLIGPTPFNIVGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215Y | D67G, K219N | G190Q | E44D, V60I, S68G, K102KR, V118I, K122E, I135V, T200TA, Q207E, R211K, L228LH, V245Q |
| >1568-30306| codons 38-247 CTELEKDGKISKIGPENPYNTPIFAIKKKGGTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKRKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVQSDLEIGQHRAKIEELREHLWKWGFYTP DNKHQKEPPFHWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |